The Control of Copy Number of IS6110 in Mycobacterium tuberculosis
نویسندگان
چکیده
منابع مشابه
The control of copy number of IS6110 in Mycobacterium tuberculosis.
Insertion sequence (IS) elements are bacterial genes that are able to transpose to different locations in the genome. These elements are often used in molecular epidemiology as genetic markers that track the spread of pathogens. Transposable elements have frequently been described as "selfish DNA" because they facilitate their own transposition, causing damage when they insert into coding regio...
متن کاملIdentification and evolution of an IS6110 low-copy-number Mycobacterium tuberculosis cluster.
A cohort of 56 patients infected with related strains of Mycobacterium tuberculosis, the S75 group, was identified in a New Jersey population-based study of all isolates with a low number of copies of the insertion element IS6110. Genotyping was combined with surveillance data to identify the S75 group and to elucidate its recent evolution. The S75 group had similar demographic and geographic c...
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15 صفحه اولTransmission dynamics and molecular characterization of Mycobacterium tuberculosis isolates with low copy numbers of IS6110.
Population-based analysis of Mycobacterium tuberculosis transmission in Houston, Tex., over 5 years identified 377 patients infected with an isolate containing one to four copies of IS6110. The isolates were analyzed by spoligotyping and assigned to one of three major genetic groups based on nucleotide polymorphisms in codons katG 463 and gyrA 95. Prospectively obtained patient interviews were ...
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ژورنال
عنوان ژورنال: Molecular Biology and Evolution
سال: 2004
ISSN: 0737-4038,1537-1719
DOI: 10.1093/molbev/msh234